If you practice bodybuilding or find yourself in other sports, you are likely to use a number of medications in addition to your workout that will contribute to accelerated results or muscle mass. These can include Proviron. Before using it, we recommend that you study its effects on your body..
Proviron (Mesterolone), the active ingredient is Mesterolone. Chemical Name: 17β-hydroxy-1α-methyl-5α-androstan-3-one-1-methyl-5α-dihydrotestosterone. A hormonal drug with moderate androgenic activity that significantly improves erection. It appeared in 1934 and is a unique anabolic despite its longevity.
The drug is a modified derivative of dihydrotestosterone (DHT), which is obtained by adding a methyl group to the first carbon (1-methyldihydrotestosterone). As previously mentioned, it is a low potency anabolic, which is why Proviron is almost always called an androgenic (or androgenic steroid). The drug has similar properties to its parent compound (DHT): once it enters muscle tissue, it is rapidly metabolized and broken down into inactive metabolites.
This is a constant problem with DHT: when it enters the muscle, the 3-hydroxysteroid dehydrogenase enzyme (found in very high concentrations in muscle tissue) binds to it and renders it inactive, converting the DHT into a compound that does not has anabolic power. This is the reason for the low anabolic power of the drug.
The known benefit of Proviron is its anti-estrogen ability. It should be noted, however, that as an aromatase inhibitor, Proviron does not have the special power of drugs such as Aromasin, Arimidex or Letrozole. But this ability still exists and can be used. Similar properties of Proviron are compared with Arimidex, although in reality its effect is not that significant.
Features and properties of Proviron
- activity: 8-12 hours (residual effect up to 24 hours);
- androgenic steroid;
- androgen index: 30-40%;
- anabolic index: 100-150%;
- does not retain water;
- low hepatotoxicity;
- does not flavor;
- It is derived from DHT but cannot be converted to DHT.
The drug is less toxic to the liver, allowing Proviron to be taken in combination with other anabolic tablets during the steroid cycle.
Its effect is to block the conversion of testosterone to estrogen, but its effectiveness in this sense is very low. Therefore, its effect is not equivalent to that of aromatase inhibitors (it will not cope with ongoing aromatization). However, Proviron actually desensitizes estrogen receptors, further increasing its effectiveness by reducing circulating estrogen.
The most significant effect is the suppression of sex hormone binding globulins. This increases the effectiveness of the course by increasing the amount of free testosterone in the blood. This occurs when testosterone in the human body is 80-98% inactive due to globulin and albumin, which bind to the sex hormone and prevent the release of testosterone. And the involvement of proviron in this ballet leads to the fact that dihydrotestosterone, which has a greater affinity for these proteins than testosterone, binds to globulin and albumin, which in turn release large amounts of free testosterone, leading to better anabolic activity. Reducing SHBG will help increase treatment outcome.
Proviron Basic functions
“Proviron” is not considered a steroid in bodybuilding, it is called a testosterone booster by most athletes. In reality, however, under the brand name “Proviron” hides the active androgen mesterolone, which in the body performs a number of functions:
- Provides a strong anabolic effect for increased protein synthesis.
- Increase the utilization of glucose in cells and reduce blood levels.
- Reduction of estrogen activity by chemical suppression of aromatase.
- Significant increase in the concentration of free testosterone in the human body.